在多发性硬化症患者之前的扩散性膜出血后,阿勒穆祖马布的重复治疗成功
Dylan Haixiang Zhao1, Gina Hadley2, Marco Pisa2
1Medical Science Division, University of Oxford, Oxford, UK.
概括
在多发性硬化症患者中,阿勒姆图祖马布可引起扩散性气泡出血 (DAH). 在一个案例中,重复治疗是可行的,这表明仔细监测可以安全地重新注射阿姆图祖马布.
科学领域:
- 神经学
- 肺病学
- 免疫学
背景情况:
- 阿拉姆图祖马布用于复发性缓解性多发性硬化症 (RRMS).
- 扩散性气泡出血 (DAH) 是阿莱姆图祖马布治疗的一个罕见,严重的并发症.
- 对于像DAH这样的不良事件后再治疗的安全性有有限的证据.
研究的目的:
- 评估在RRMS患者之前经历过DAH治疗的可行性和安全性.
- 提供证据支持阿勒姆图祖马布诱导的DAH的再治疗策略.
主要方法:
- 一个29岁的女性患有RRMS,在她的第一个Alemtuzumab周期中发展了DAH.
- 经过跨学科的咨询,患者在一年后重新接受了阿勒姆图祖马布治疗.
- 通过定期实验室和放射检查进行密切监测.
主要成果:
- 患者在重新接受阿勒姆图祖马布治疗后没有出现DAH复发.
- 这表明在某些特定情况下可以考虑重新治疗.
结论:
- 在以前经历过DAH的RRMS患者中,可以重复治疗.
- 仔细监测和低调查门对于安全的再处理至关重要.
- 这一案例增加了支持重新注射阿姆图祖马布的有限证据.
更多相关视频
09:52Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma
Published on: January 25, 2015
13.5K
07:21Processing of Bronchoalveolar Lavage Fluid and Matched Blood for Alveolar Macrophage and CD4+ T-cell Immunophenotyping and HIV Reservoir Assessment
Published on: June 23, 2019
21.4K
相关概念视频
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
44
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
44
Pneumothorax-II
355
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Clinical Manifestations:
355
