预后营养指数是穿孔性胃潰瘍手术中的患病率和死亡率的有用预测标记
1Department of General Surgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu Province, People's Republic of China.
预后营养指数 (PNI) 有效预测紧急穿孔性胃潰瘍 (PPU) 手术的结果. 较低的PNI分数表明患病率和死亡率的风险较高,有助于术后管理.
科学领域:
- 手术结果研究
- 危急疾病中的营养标志物
- 胃肠道手术并发症
背景情况:
- 穿孔性胃潰瘍 (PPU) 的緊急手術與嚴重的罹病率和死亡率有關.
- 预后营养指数 (PNI) 在PPU手术结果中的预后价值需要进一步调查.
- 在各种手术患者群体中,PNI是已验证的预测结果.
研究的目的:
- 评估预后营养指数 (PNI) 在接受PPU紧急手术的患者的术后发病率和死亡率的有效性.
- 确定PNI是否可以作为PPU患者的可靠风险分层工具.
主要方法:
- 从2018年到2023年进行紧急PPU手术的320名患者的回顾性分析.
- 使用多变量逻辑回归来确定疾病和死亡率的独立预测因素.
- 使用接收器操作特征 (ROC) 曲线分析评估了PNI的预测性能.
主要成果:
- 总体发病率和死亡率分别为26. 6%和17. 8%.
- 低PNI是增加发病率 (OR1. 05) 和死亡率 (OR1. 09) 的独立预测因素.
- 较高的PNI得分与明显较低的发病率和死亡率相关 (死亡率AUC: 0. 81;发病率AUC: 0. 73).
结论:
- 预后营养指数 (PNI) 是针对穿孔性胃潰瘍进行手术的患者患病率和死亡率的有价值和可靠预测指标.
- 将PNI纳入风险评估方案可以提高PPU患者的外科治疗策略.
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