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在过敏性鼻炎中,RGS1通过调节NF-κB/AQP5轴诱导鼻上皮质屏障功能障碍

Wenchuan Chang1, Yan He2, Liang Liu1

  • 1Department of Otolaryngology, Children's Hospital of Soochow University, No.92, Zhongnan Street, Wuzhong Industrial Park, Wuzhong District, Suzhou, 215025 China.

Cytotechnology
|August 20, 2025
PubMed
概括

在过敏性鼻炎 (AR) 中,G蛋白信号调节剂1 (RGS1) 升高. 沉默RGS1通过增加AQP5表达和抑制NF-κB通路来保护鼻上皮质屏障功能,为AR提供潜在的治疗点.

关键词:
在AQP5过敏性鼻炎表皮屏障功能障碍在 NF-κB一个RGS

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