性多重体疫苗通过诱导局部细胞死亡来增强抗原特异性细胞毒性T细胞反应

David J Peeler1, Albert Yen1, Nicholas Luera1

  • 1Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.

Advanced therapeutics
|August 20, 2025
PubMed
概括

VIPER疫苗纳米载体提供抗原并破坏内体,增强细胞毒性T细胞反应. 然而,改善交叉呈现需要VIPER诱导的细胞死亡,这表明需要进一步研究以获得最佳的疫苗输送.

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