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在黑人中延迟诊断子宫内膜癌的危险因素:来自GUIDE-EC研究的结果

Maya E Gross1, Mindy Pike1, Julianna Alson1

  • 1Department of Obstetrics and Gynecology, Fred Hutchinson Cancer Center, University of Washington, USA.

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五分之一的黑人患有子宫内膜癌 (EC) 患者面临延迟诊断. 术前超声波的使用与这些延迟密切相关,这表明需要更早地采集组织样本.

关键词:
诊断情况子宫内膜癌医疗保健质量种族差异通过阴道的超声波

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科学领域:

  • 癌症学
  • 公共卫生
  • 健康上的差异

背景情况:

  • 患有子宫内膜癌 (EC) 的黑人患者在晚期被诊断出不成比例.
  • 识别导致诊断延迟的因素对于改善结果至关重要.

研究的目的:

  • 在黑人患者中确定与子宫内膜癌 (EC) 延迟诊断相关的变量.
  • 调查种族和组织学之外的因素,增加了延迟EC诊断的风险.

主要方法:

  • 对388名黑人患者进行的回顾性研究 (2014 - 2020年).
  • 延迟诊断定义为诊断时间超过28天.
  • 使用描述性统计,单变量回归和因子分析.

主要成果:

  • 20% 的患者经历了延迟诊断.
  • 手术前的超声波与延迟诊断有很强的联系 (OR 4. 4).
  • 高BMI (≥40) 也与延迟诊断 (OR1. 9) 相关.

结论:

  • 延迟诊断影响了相当一部分黑人患者.
  • 手术前的超声波是延迟EC诊断的一个关键因素.
  • 首先采用组织采样方法可以改善黑人风险患者的早期诊断.