饮食中的植物化学指数和胆结石疾病的风险:个案对照研究
Zeinab Ghaeminejad1,2, Leyli Zahra Bahreini Boroujeni1,2, Fatemeh Javaheri-Tafti1,2
1Student Research Committee Shahid Beheshti University of Medical Sciences Tehran Iran.
Health science reports
|August 20, 2025
概括
通过饮食中的植物化学指数 (DPI) 来衡量植物化学物质的摄入量较高,与胆结石疾病 (GSD) 的风险降低有关. 这表明富含植物化合物的饮食可能有助于预防胆结石.
科学领域:
- 胃肠病学
- 营养科学
- 流行病学
背景情况:
- 胆结石病 (GSD) 是一种由遗传和代谢因素影响的常见胃肠道疾病.
- 肥胖,胰岛素耐药性和脂质障碍有助于增加GSD的发病率,并且可以通过饮食来改变.
- 饮食中的植物化学指数 (DPI) 反映了生物活性植物化合物的摄入量,这可能会影响GSD风险.
研究的目的:
- 调查饮食中的植物化学指数 (DPI) 与胆结石疾病 (GSD) 风险之间的联系.
主要方法:
- 一项涉及189名GSD患者和342名对照者的病例对照研究.
- 用168项食物频率问卷来计算DPI的饮食摄入量.
- 用于确定概率比率 (OR) 和95%置信区间 (CI) 的后勤回归模型,对混因素进行调整.
主要成果:
- 增加DPI得分显示GSD病例显著减少 (p < 0. 001).
- 在原始和调整后的分析中,较高的DPI得分与较低的GSD风险显著相关 (OR 0. 30;95% CI: 0. 19- 0. 52).
结论:
- 在DPI和GSD风险之间存在显著的反向关联.
- 富含植物化学物质的食物可能具有防止胆结石形成的保护性.
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