德国办公室肺病学家对耐火或无法解释的慢性咳患者进行横截面评估
Peter Kardos1, Heinrich Worth2, Ulrich Koehler3
1Lungenzentrum Frankfurt, Frankfurt am Main, Germany.
Frontiers in medicine
|August 20, 2025
概括
耐药性慢性咳 (RCC) 和不明原因的慢性咳 (UCC) 分别影响德国人口的0.21%和0.64%. 这项研究强调女性患病率较高,诊断时间较长.
科学领域:
- 肺病学
- 流行病学
- 临床医学
背景情况:
- 慢性咳 (CC) 是一个常见的临床症状.
- 耐火性慢性咳 (RCC) 和无法解释的慢性咳 (UCC) 是由欧洲指南定义的不同的实体.
- 在德国门诊肺病诊所中RCC/ UCC的患病率以前是未知的.
研究的目的:
- 调查德国肺病专家诊断的成人门诊患者中RCC/UCC的患病率.
- 确定患者人口统计和常见的RCC/UCC治疗方法.
主要方法:
- 在16个德国肺部病房进行了横截面观察研究.
- 包括诊断为RCC或UCC的成年患者;不包括活跃吸烟者.
- 基于DGP的指导方针进行了流行分析.
主要成果:
- 在22140名查患者中,421人符合条件,226人符合RCC/ UCC标准.
- 在德国,RCC/ UCC的患病率分别为0. 21%和0. 64%.
- 大多数患者是女性 (71. 3%),治疗耐药性慢性咳 (TRCC) 是最常见的 (77. 9%),通常与喘或GERD有关. 诊断延迟时间平均为6.4年.
结论:
- 这是第一次估计德国二级护理门诊患者的RCC/UCC患病率.
- 在女性中观察到更高的患病率,诊断延迟显著.
- 研究结果强调需要改善RCC/UCC的诊断和治疗策略.
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