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Updated: Sep 8, 2025

Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients
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可移植元素的遗传和表观遗传重编程驱动eCDNA介导的转移性前列腺癌

Lisanne Mout1, Thaidy Moreno-Rodriguez2, Giacomo Grillo1

  • 1Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.

bioRxiv : the preprint server for biology
|August 20, 2025
PubMed
概括

外染色体DNA (ecDNA) 通过放大瘤基因来驱动癌症的进化. 在前列腺癌中,LINE1重复在ecDNA上激活AR基因,导致治疗耐药性.

关键词:
ATAC ATAC ATAC ATAC ATAC ATAC ATAC ATAC ATAC ATAC ATAC ATAC ATAC ATAC ATAC ATAC ATAC ATAC ATAC ATAC ATACBFBB BFBB BFBB BFBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBB染色是一种染色素.在HiC中,HiC就是HiC.第1行 一线在WGS中,使用的是WGS.受体受体是受体的受体.割抵抗性前列腺癌是什么ecDNADNA ecDNADNA是什么意思内生重复的元素是内生重复的.增强剂是一种增强剂.这是表观遗传学.在表观基因组中,表观基因组是表观基因组的.前列腺癌是前列腺癌.转录因子是一种转录因子.可转移的元素可以转移.变种变种的变种

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