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Updated: Sep 8, 2025

Author Spotlight: An Integrated Workflow to Study the Promoter-Centric Spatio-Temporal Genome Architecture in Scarce Cell Populations
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Published on: April 21, 2023

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KSHV编码的vIRF3与细胞IRF4合作,通过复杂的DNA元素驱动超级增强器活动

Ziyan Liang, Haocong Katherine Ma, Christine B Magdongon

    bioRxiv : the preprint server for biology
    |August 20, 2025
    PubMed
    概括

    卡波西的肉瘤相关疹病毒 (KSHV) 瘤蛋白vIRF3通过将复杂的DNA元素与细胞IRF4结合来激活瘤性超级增强剂 (SE). 这种相互作用对于原发性输出淋巴瘤 (PEL) 细胞存活和瘤基因激活至关重要.

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