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Updated: Sep 8, 2025

Author Spotlight: Advancements in Molecular Biomarker Testing for Non-Squamous Non-Small Cell Lung Cancer
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在非小细胞肺癌中的新型预测空间生物标志物:利基的多样性解锁治疗敏感性 (DONUTS)

Tricia R Cottrell1, Jeffrey S Roskes2,3,4, Michael Fotheringham1

  • 1Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada.

bioRxiv : the preprint server for biology
|August 20, 2025
PubMed
概括

一个新的生物标志物,的多样性解锁治疗敏感性 (DONUTS),预测肺癌治疗反应. 这种空间模型识别了CD8+T细胞,改善了临床使用的单细胞标记物.

关键词:
在AstroPath上使用.在CD8+FoxP3+中使用.在NSCLCLC中,我们可以看到NSCLCLC.在PD-1中使用PD-1.生物标志物生物标志物免疫疗法 免疫疗法肺癌是一种肺癌.邻里社区 邻里社区病理学的病理学一个空间的空间.

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In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
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