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Updated: Sep 8, 2025

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多巴胺D3受体的Go/z偏差合特征

Lucrezia Zanetti1, Luca Franchini1, Shirsha Saha1

  • 1Department of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, NY 14642.

bioRxiv : the preprint server for biology
|August 20, 2025
PubMed
概括

与其他多巴胺受体不同,多巴胺D3受体 (D3R) 不会激活Gi蛋白质. 这种由特定的分子相互作用驱动的选择性信号影响神经生理反应和治疗设计.

关键词:
在 D3RG蛋白结合受体 (GPCR)基于细胞的测试多巴氨基系统神经药理学

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