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Updated: Jun 15, 2026

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人类皮层内微刺激:十年的安全性和有效性

Charles M Greenspon1, Taylor G Hobbs2,3, Ceci Verbaarschot2,4,5,6

  • 1Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL, USA.

medRxiv : the preprint server for health sciences
|August 20, 2025
PubMed
概括

皮层内微刺激 (ICMS) 在脊髓损伤 (SCI) 患者中安全地恢复了触觉,长达10年. 这项长期研究表明ICMS是一种有前途的神经调节装置,用于感官恢复.

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Toxicity Testing in Animals01:23

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...