肺血管功能障碍在慢性阻塞性肺病中的重要性
Steven D Nathan1, Lucilla Piccari2, Steven H Abman3
1Advanced Lung Disease and Transplant Program Inova Schar Heart and Vascular Institute Falls Church Virginia USA.
慢性阻塞性肺病 (COPD) 的肺血管功能障碍是常见的,经常被低诊断. 需要更多的研究和临床试验来解决COPD管理中的这一重大未满足需求.
科学领域:
- 心血管医学
- 呼吸系统医学
- 肺高血压
背景情况:
- 慢性阻塞性肺病 (COPD) 经常与肺血管异常有关.
- 这些异常从轻微的功能障碍到严重的肺高血压.
- 在全球范围内,肺血管功能障碍对COPD的影响可能被低估.
研究的目的:
- 突出肺血管在COPD中的作用.
- 提高对COPD肺血管功能障碍的认识.
- 刺激进一步的研究和临床试验.
主要方法:
- 肺血管研究所创新药物开发计划 (PVRI IDDI) 第三组肺高血压工作流的审议.
- 对COPD肺血管系统现有知识的审查.
- 确定研究和治疗的未满足需求.
主要成果:
- 肺血管异常是COPD的一个显著的,被低估的并发症.
- 包括肺高血压在内的各种血管功能障碍.
- 许多地区的资源有限, 阻碍了对问题的准确评估.
结论:
- 肺血管功能障碍是COPD的一个关键方面.
- 包括临床试验在内的更多研究是必不可少的.
- 解决这一未满足的需求可以改善COPD患者的治疗结果.
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