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Updated: Sep 8, 2025

Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients
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选择性氨基酸配方增强阴离子分泌并恢复囊性纤维化突变的功能

Astrid Grosche1, Anusree Sasidharan1, Matthias Salathe2

  • 1Department of Radiation Oncology, University of Florida, Gainesville, FL, United States.

Frontiers in pharmacology
|August 20, 2025
PubMed
概括

一种新的选择性氨基酸配方 (SAA) 增强了囊性纤维化 (CF) 细胞中的离子分泌,不论突变类型如何. 这种SAA疗法有望改善CFTR功能和呼吸道表面液体平衡.

关键词:
美国其他类型氨基酸化物分泌囊性纤维化人类支气管上皮细胞

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