在接受放射治疗的头癌患者的预防性消化不良干预中使用的患者报告的结果措施:系统性审查
Janet Varghese1, Riya Jacob2, Jisha B Krishnan3
1Department of Speech and Hearing, Manipal College of Health Professions, Manipal Academy of Higher Education (MAHE), Manipal, India.
Logopedics, phoniatrics, vocology
|August 20, 2025
概括
这次审查评估了患者报告的头癌患者的治疗结果 (PROM). 虽然临床结果有所改善,但PROMs没有显著变化,这凸显了需要仔细选择PROM.
科学领域:
- 癌症学
- 康复医学
- 健康成果研究
背景情况:
- 食障碍是非手术治疗头癌的常见副作用.
- 预防性干预旨在缓解食欲障碍,但其有效性需要严格评估.
- 患者报告的结果测量 (PROM) 对于从患者的角度评估治疗影响至关重要.
研究的目的:
- 系统地识别和评估用于头癌患者的预防性消化障碍干预研究中的PROM.
- 评估这些PROM的质量和发育特征.
- 分析干预措施对患者报告的消化不良结果的影响.
主要方法:
- 对五个数据库进行系统审查 (PubMed,科学网络,Pro-Quest,CINHAL,SCOPUS).
- 在接受非手术治疗的头部和部癌症患者中对食障碍进行干预研究.
- 对已识别的PROM心理发展的研究进行单独分析.
主要成果:
- 评估了17个PROM的16个干预研究和20个发展研究.
- 最常使用的PROM包括MD安德森消化症清单和EORTC QLQ-C30/H&N35.
- 在构造和发展方面,PROMs表现出变化;没有一个符合所有测量标准.
结论:
- 虽然临床医生评价的结果显示了干预效益,但患者报告的结果没有显示出干预前后的显著变化,尽管观察到改善的趋势.
- 根据发育特征和测量领域,PROMs的扩散需要仔细选择.
- 需要进行进一步的研究,以调查患者报告的消化不良得分的改善趋势,并完善在临床实践中使用PROM.
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