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在Charcot-Marie-Tooth疾病的三种小鼠模型中的SARM1抑制

Alaura D Rice1, Abigail L D Tadenev1, Timothy J Hines1

  • 1The Jackson Laboratory, Bar Harbor, Maine, USA.

Journal of the peripheral nervous system : JPNS
|August 20, 2025
PubMed
概括

在三种Charcot-Marie-Tooth病 (CMT) 鼠标模型中,SARM1抑制没有改善轴突退化. 需要进一步研究以确定哪些CMT亚型可能受益于SARM1抑制疗法.

关键词:
其他类型在NMNAT2美国轴突退化无菌的阿尔法和TIR图案含有1

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