老龄化和血糖控制对2型糖尿病老年人可能发生的肉症的性别特异性影响:横截面研究
Yi-Fang Huang1,2,3, Shih-Ping Liu4,5, Chih-Hsin Muo6
1Department of General Dentistry, Chang Gung Memorial Hospital, Linkou, 33305, Taiwan.
Aging clinical and experimental research
|August 20, 2025
概括
患有2型糖尿病 (T2DM) 的老年妇女可能面临更高的肉症风险. 有效的血糖控制是预防的关键,特别是当与高血压或心脏病等疾病相结合时.
科学领域:
- 老年学
- 内分泌学
- 代谢疾病
背景情况:
- 在老年人群中, Sarcopenia 越来越令人担忧.
- 2型糖尿病 (T2DM) 在老年人中很常见.
- 老龄化,血糖控制和肉症之间的相互作用需要进一步研究.
研究的目的:
- 检查T2DM老年人的血糖控制和肉之间的性别相关性.
- 研究衰老和血糖控制对肉症风险的协同效应.
- 在T2DM患者中发现加剧了肉症风险的并发症.
主要方法:
- 在台湾对5728名60岁以上的社区成年人进行了横截面研究.
- 根据2019年亚洲肉类症工作组的标准对肉类症进行分类.
- 逻辑回归分析以确定可能的肉眼的性别特异概率 (ORs).
主要成果:
- 患有T2DM的老年女性可能患有肉症的几率显著增加 (OR=2. 07).
- 在70岁以上的女性中,良好的血糖控制和不良的血糖控制都与肉症的风险增加相关.
- 高血压,缺血性心脏病 (IHD) 和抑郁症与较高的肉类的几率有关,特别是在血糖控制较差的情况下.
结论:
- 血糖控制对于预防T2DM老年妇女可能发生的肉症至关重要.
- 伴随性疾病如高血压,心血管疾病和抑郁症在血糖控制不良的T2DM患者中增加了肉症的风险.
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