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对食道癌与同步前淋巴结转移的诱导治疗后转化手术的结果:多机构回顾性研究

Koji Tanaka¹, Keijiro Sugimura², Norihiro Matsuura³

¹Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan. ktanaka@gesurg.med.osaka-u.ac.jp.

Annals of surgical oncology

|August 20, 2025

概括

胃肠癌转化手术可行且有前途. 为了改善这些患者的长期生存结果,控制结节状况,包括副大动脉淋巴结,至关重要.

科学领域:

癌症学
外科瘤学
胃肠道瘤学

背景情况:

系统化疗是远程转移的食道癌症的标准治疗方法,包括准大动脉淋巴结转移.
在这种情况下,转化手术的作用仍有争议.

研究的目的:

评估诱导治疗后同步PALN转移的食道癌转换手术的临床结果.

主要方法:

一个多机构的回顾性研究,对48名同步PALN转移的食道癌患者进行了研究.
患者接受了诱导化疗或化疗放射治疗,随后进行转换手术 (2005 - 2022年).

主要成果:

在诱导治疗后,48名患者接受了分泌管切除术;45名患者接受了化疗,3名患者接受了化疗放射治疗.
术后并发症率为48%,住院死亡率为2%.
3 年和 5 年的总生存率分别为 36. 1% 和 25. 2%. 病理结节状态和最终的PALN状态是独立的预后因素.

结论:

对同步PALN转移的食道癌的转化手术显示可行性和有希望的结果.
控制结节状况,包括PALN转移,对于有利的长期预后至关重要.

关键词:

转换手术食道癌症甲状腺淋巴结

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