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Updated: Sep 10, 2025

A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1
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双重DNA和RNA特异性的结构基础是G-四重复溶解的DEAH盒酶DHX36

Michael T Banco1, Tapas Paul2, Jiansen Jiang1

  • 1Biochemistry and Biophysics Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Cell reports
|August 20, 2025
PubMed
概括

DEAH盒子酶36 (DHX36) 可以分解DNA和RNA的G四重复. 结构和运动研究揭示了特定的域和循环如何使DHX36能够区分DNA和RNA基质.

关键词:
亚太酶的使用CP:分子生物学低温样本电子显微镜一个分子超级家族2四分之一四重复的

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