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Updated: Sep 10, 2025

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
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Published on: January 24, 2016

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交替拼接的IRF7异型对干扰素的表达有不同的调节,以调整对病毒感染的反应

Asmita Panthi1, Max B Ferretti2, Olivia Howard2

  • 1Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Pharmacology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Cell reports
|August 20, 2025
PubMed
概括

干扰素调节因子7 (IRF7) 的替代拼接产生一种新的蛋白质形式. 这种exIRF7比标准cIRF7更有效地增强对病毒的免疫反应,改善先天免疫力.

关键词:
CELF2 在CP:免疫学其他国家/地区替代拼接天生的免疫力干扰素内部保留蛋白质二元化转录激活

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