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通过 CD8+ T 细胞抑制,CX3CR1+ 巨与 HSC 相互作用促进 HCC

Jong-Min Jeong1, Sung Eun Choi1, Young-Ri Shim1

  • 1Laboratory of Liver Research, Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea.

Hepatology (Baltimore, Md.)
|August 20, 2025
PubMed
概括

通过激活CX3CR1+巨细胞,肝星细胞促进肝细胞癌 (HCC). 这些巨细胞中的视网蛋白诱导酶-1,抑制CD8+T细胞并驱动瘤生长.

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