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Updated: Sep 10, 2025

Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage
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Published on: January 31, 2018

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在肢体发育过程中,RPA1可保护DNA损伤诱导的PANoptosis

Qi Yin1, Shuanglin Peng1, Zhong Zhang1

  • 1State Key Laboratory of Oral Diseases & National Center for Stomatology and National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan, China.

Science advances
|August 20, 2025
PubMed
概括

在胚胎发育期间的基因组不稳定是危险的. 这项研究表明,当DNA受损时,RPA1通过ZBP1依赖的PANoptosis防止细胞死亡,从而保护四肢发育.

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