怀孕期间严重的COVID-19:对101例患者队列的呼吸系统结果的评估
Isabel Cristina Melo Mendes1,2, Ana Luiza Martins de Oliveira2, Priscila Martins Pinheiro Trindade3
1Universidade Federal do Rio de Janeiro, Programa de Pós-Graduação em Doenças Infecciosas e Parasitárias, Rio de Janeiro, Rio de Janeiro, Brazil.
孕妇和产后妇女面临严重的COVID-19风险,经常需要密集护理,侵入性机械通风和神经肌肉阻断剂. 公共卫生政策必须优先考虑这一高风险群体.
科学领域:
- 传染性疾病 传染性疾病
- 临界护理医学 临界护理医学
- 孕产妇健康 孕产妇健康
背景情况:
- 孕妇和产后妇女患重症COVID-19的风险更高.
- 关于这种人口中的疾病进展和管理的数据有限.
- 在孕妇和产后患者中,严重的COVID-19需要进入重症监护室 (ICU).
研究的目的:
- 描述因严重COVID-19而入住ICU的孕妇和产后妇女的社会人口统计学,临床和放射学特征.
- 为了强调这个高风险人群的呼吸系统结果.
- 为孕妇和产后妇女的COVID-19管理提供公共卫生策略的信息.
主要方法:
- 追溯性,描述性的队列研究.
- 包括从2020年5月到2022年6月连续接收孕妇和产后妇女进入传染病ICU.
- 对社会人口学,临床和放射学数据的分析,包括呼吸辅助.
主要成果:
- 101例住院病例 (85例孕妇,16例产后病例);大多数是在妊娠的第二/第三季度.
- 46.5%需要侵入性机械通风 (IMV),其中62.1%的CT扫描显示>50%的肺部参与.
- 死亡率为整体15.8%,需要IMV的患者为34.0%.
结论:
- 孕妇和产后妇女面临严重COVID-19的重大风险.
- 高率的IMV和神经肌肉阻塞表明疾病的严重程度.
- 公共卫生政策中的优先考虑对于这个弱势群体至关重要.
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