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Updated: Sep 10, 2025

Bioengineering of Humanized Bone Marrow Microenvironments in Mouse and Their Visualization by Live Imaging
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白血病细胞通过CaV1.2-依赖机制劫持流体生物电力来重新编程骨髓

Ambra Da Ros1, Maddalena Benetton1, Giulia Borella1

  • 1Department of Women's and Children's Health, Onco-Hematology lab and clinic, University of Padova, Padova, 35128, Italy.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|August 20, 2025
PubMed
概括

儿童急性髓性白血病 (AML) 爆发通过改变其生物电特性,特别是膜电位和通道表达,重新编程健康的介质层细胞 (MSC). 恢复MSC的正常电功能可能会逆转白血病支持作用.

关键词:
急性骨髓性白血病生物电力介质层细胞瘤微环境电压膜潜力

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