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Updated: Sep 10, 2025

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
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Published on: August 22, 2018

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基于亚糖的硫胺类药物的研究:一种新的碳酸无水酶抑制剂

Debora Pratesi1, Francesco Brenzini Biagioni1, Camilla Matassini1

  • 1Dipartimento di Chimica 'Ugo Schiff', Università degli Studi di Firenze, via della Lastruccia 3-13, Sesto Fiorentino, FI 50019, Italy.

Bioorganic chemistry
|August 20, 2025
PubMed
概括

研究人员探索了人类碳酸酶 (hCA) 抑制的新型阿扎糖衍生物,发现去除三醇环增强了与瘤相关的hCA IX和其他临床相关异型的抑制.

关键词:
硫胺碳酸无水葡萄糖仿制剂选择性抑制类植物三醇尿素

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