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在老年小鼠中抑制PPP1R3G会损害OPC的分化和髓化

Zhao-Wei Feng1, Xu Miao2, Hao Shi2

  • 1Department of Neurology, The Second Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.

International immunopharmacology
|August 20, 2025
PubMed
概括

蛋白酸酶1调节子单元3G (PPP1R3G) 的下降会影响大脑衰老和认知. 通过支持寡干细胞前体细胞分化和线粒体健康,恢复PPP1R3G促进髓化和认知功能.

关键词:
AMPK-Drp1信号认知能力下降线粒体动力学骨髓化基细胞前体细胞其他类型

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