,HPVDNA

Megan Tang1, Max Dougherty2, Leslie Worona2

  • 1Department of Hematology/Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, United States; Department of Otolaryngology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

Oral oncology
|August 20, 2025
PubMed
概括

人类乳头瘤病毒阳性口腔状细胞癌 (HPVOPC) 诱导治疗期间瘤组织修饰病毒 (TTMV) 清除的延迟预示着治疗失败. 早期的TTMV清除与更好的结果有关,这表明其在指导治疗中的有用性.

相关概念视频

Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.3K
Adaptive Mechanisms in Cancer Cells02:53

Adaptive Mechanisms in Cancer Cells

Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
5.8K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
7.1K