为什么核心结果集不被使用 - - 传播和实施科学如何帮助
1Department of Orthopaedic Surgery, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
The Journal of surgical research
|August 20, 2025
概括
在外科研究中实施核心成果集 (COS) 需要一个传播和实施 (D&I) 框架. 这种方法解决了障碍,并促进了标准化结果报告的采用.
科学领域:
- 实施科学
- 外科研究
- 健康问题
背景情况:
- 核心结果集 (COS) 标准化了结果报告,但在临床实践中很少被采用.
- 实施COS的障碍包括工作流的整合和利益相关者的参与.
- 标准化结果集对于试验可比性和反映患者优先事项至关重要.
研究的目的:
- 通过传播和实施 (D&I) 科学,提出实施COS在外科研究中的概念框架.
- 将这一框架应用于外围神经损伤 (PNI) 的新核心结果集.
主要方法:
- 整合三个D&I工具:实施研究的综合框架,实施变革的专家建议以及范围,有效性,采用,实施和维护 (RE-AIM).
- 这些工具指导计划,识别障碍,并选择采用COS的策略.
- 一个新开发的PNI COS是框架应用的实际案例.
主要成果:
- 该框架使用实施研究的综合框架确定了背景障碍.
- 通过"实施变革的专家建议"提出了诸如冠军参与和电子健康记录整合等可行的策略.
- 该RE-AIM模型提供了评估COS采用和长期可持续性的指标.
结论:
- 从一开始就嵌入研发创新策略对于弥补COS实施差距至关重要.
- 拟议的框架为复杂的外科环境中采用COS提供了可通用的方法.
- 需要进一步的研究来定制跨外科子专业的实施策略.
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