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登革热脑炎:一个突显神经复发症和诊断挑战的病例

Haripriya Sivakumar¹, K Sultan Basha¹, Balamurugesan Kandan²

¹Department of Microbiology, JIPMER, Puducherry 605006, India.

Diagnostic microbiology and infectious disease

|August 20, 2025

概括

一位年轻女子患上严重的登革热脑炎, 早期诊断和支持性护理对于治疗这种危及生命的神经系统疾病至关重要.

科学领域:

神经学
传染性疾病
病毒学

背景情况:

登革热病毒感染可能导致严重的神经并发症,包括脑炎.
登革热脑炎是严重的公共卫生问题,特别是在流行地区.

研究的目的:

在一个年轻的成年女性报告登革热脑炎病例.
突出临床表现和诊断上的困难.
强调严重登革热及时干预的重要性.

主要方法:

一个20多岁的女性患者的病例报告.
临床观察和实验室调查,包括NS1抗原测试和CSFPCR.
神经成像 (MRI/CT) 来评估大脑的参与.
对疾病进展和对支持性治疗的反应进行监测.

主要成果:

患者出现了发烧,头痛,吐和感官变化,进展为脑病变.
最初的测试显示白细胞症,血小板减少和肝酶升高.
登革热NS1抗原和DENV-2PCR证实了该诊断.
脑部成像显示了脑膜胀, 进展到出血和扩散脑胀.
尽管得到了支持,但病情迅速恶化,并死于疾病.

结论:

登革热脑炎是一种严重的症状,需要高度的临床怀疑.
通过NS1抗原和PCR等先进诊断的早期检测至关重要.
迅速提供支持性护理和治疗对于改善严重登革热病例的结果至关重要.
这一案例强调了在诊断和管理登革热脑炎时需要保持警.

关键词:

登革热脑炎神经系统并发症

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