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Updated: Sep 10, 2025

Measuring Relative Insulin Secretion using a Co-Secreted Luciferase Surrogate
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调节受体活动的蛋白3增强GLP-1介导的胰岛素分泌

Abigail Pearce1, Poonam Kumari2, Claudia M Sisk1

  • 1Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1PD, UK.

The Journal of biological chemistry
|August 20, 2025
PubMed
概括

受体活性修饰蛋白3 (RAMP3) 调节类似葡萄糖-1受体 (GLP-1R) 信号,增强胰岛素分泌. 这种相互作用可能会减少与目前用于糖尿病和肥胖的GLP- 1R疗法的副作用.

关键词:
其他法规细胞内释放的糖尿病G 与蛋白质结合的受体第二个使者胰岛素分泌

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