自我报告的步行节奏与癌症发病率和死亡率的关联:妇女健康加速计协作
Cami N Christopher1,2,3, Kelly R Evenson4, Annie Green Howard5,6
1Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Journal of physical activity & health
|August 20, 2025
概括
步行速度较慢可能会增加老年妇女患癌症的风险. 随便步行与较快步行相比,与乳腺癌和不活动相关癌症的风险更高有关.
科学领域:
- 老年学是指老年学的学科.
- 流行病学 流行病学
- 在瘤学瘤学.
背景情况:
- 步行对健康的好处已经确立,但步行速度对癌症结果的影响仍然不清楚.
- 了解身体活动强度 (如步行节奏) 与癌症风险之间的关系对于公共健康至关重要.
- 这项研究解决了关于老年妇女步行节奏和癌症发病率和死亡率的知识差距.
研究的目的:
- 检查自我报告的步行速度与癌症发病率和死亡率之间的关联.
- 这项研究重点关注女性健康加速计协作中的62至99岁的女性.
- 研究不同步行步伐 (快速,平均,随意,非步行者) 与癌症结局的关系.
主要方法:
- 利用来自老年女性队伍的自我报告的步行速度数据.
- 采用多变量分层的Cox比例危险模型来分析癌症的结果.
- 随访参与者平均8.0年,以确定癌症发病率和死亡率.
主要成果:
- 在步行速度和总体癌症发病率或死亡率之间没有发现显著的关联.
- 与快速步行相比,随便步行速度显示出与不活动相关的癌症 (HR 1.21) 和乳腺癌 (HR 1.40) 的综合风险更高.
- 对结肠癌,子宫内膜癌和肺癌的单独分析没有显示出与步行节奏的显著关联.
结论:
- 与更快的步伐相比,慢步的步伐可能与绝经后妇女患某些癌症的风险增加有关.
- 这些发现表明,步行节奏降低与癌症风险增加之间存在潜在联系,特别是乳腺癌和与不活动相关的癌症.
- 需要进一步的研究来证实这些关联,并探索潜在的生物机制.
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