在内炎管理研究中的急性真菌性白内障后内炎:EMS报告7
Taraprasad Das1, Akash Belenje2, Joveeta Joseph3
1Anant Bajaj Retina Institute, Srimati Kanuri Santhamma centre for Vitreoretinal Diseases, LV Prasad Eye Institute, Hyderabad, Telangana, India tpdbei@gmail.com.
BMJ open ophthalmology
|August 20, 2025
概括
急性白内障后真菌内炎影响印度近10%的患者,角膜疹表明风险更高. 真菌感染对常见的抗真菌药物表现出耐药性,需要进行敏感性测试.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 白内障手术是一种常见的手术,但可能会出现诸如内炎等并发症.
- 性内炎是一种严重的眼内感染,可能导致视力丧失.
- 早期诊断和适当的治疗对于治疗白内障后内炎至关重要.
研究的目的:
- 为了研究和描述急性白内障后的真菌内.
- 基于微生物学诊断方法 (培养与测序) 的临床结果进行比较.
- 评估真菌内的抗真菌耐药性模式.
主要方法:
- 从Endophthalmitis管理研究中对急性白内障后真菌内炎患者的回顾性分析.
- 使用常规和分子微生物学证实真菌感染.
- 临床评估包括视力敏度,眼内压力和炎症评分.
- 抗真菌易感性测试. 抗真菌易感性测试.
主要成果:
- 内发生在9.5%的急性白内障后内病例中.
- 培养阳性病例显示炎症增加,视力恶化,干预需求增加.
- 常见的真菌包括*Fusarium*和*Aspergillus* spp.,观察到具有显著的抗真菌耐药性.
结论:
- 在印度,急性白内障后真菌内炎的发病率很高,特别是在角膜的病例中.
- 分子方法有助于诊断,但由于检测出非活性的生物体,需要仔细解释.
- 多种抗真菌耐药性突出显示了常规敏感性测试的必要性.
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