中枢神经系统的单侧原发性血管炎:一种罕见且未被认可的实体
Pranjal Rai1, Neetu Soni1, Shreya Sri Gopikonda1
1From the Department of Neuroradiology, Mayo Clinic, Rochester, MN (P.R., J.C.B, T.J.P, F.E.D, S.A.M, M.M.S, G.B.), Department of Radiology, Mayo Clinic, Jacksonville, FL (N.S.), Employee State Insurance Corporation (ESIC) Hospital, Hyderabad, Telangana, India (S.S.G) and Department of Radiology, MD Anderson Cancer Center, Houston, TX (A.A.).
AJNR. American journal of neuroradiology
|August 20, 2025
概括
中枢神经系统的单边原发性血管炎 (U-PACNS) 是一种罕见的疾病,经常被误诊. 早期识别和治疗对于这种未被认可的血管炎的更好的结果至关重要.
科学领域:
- 神经学 神经学
- 免疫学 免疫学 免疫学
- 血管医学 血管医学
背景情况:
- 中枢神经系统的原发性血管炎 (PACNS) 是一种罕见的血管炎,影响大脑和脊髓.
- PACNS的一个子集呈现出严格单边的参与 (U-PACNS),由于质瘤,脱髓化或脑炎的重叠特征,往往被误诊.
研究的目的:
- 审查中枢神经系统 (U-PACNS) 单侧原发性血管炎的罕见和未被认可的实体.
- 概述关键的成像特征和差异诊断,以帮助及时,准确的U-PACNS的非侵入性诊断.
主要方法:
- 对报告的U-PACNS病例进行文献综述.
- 临床和成像特征的分析.
- 与差异诊断进行比较.
主要成果:
- U-PACNS可以表现为类似瘤的病变,心脏病发作或出血.
- 图像检测结果,包括VWI,往往是非特定的.
- 组织病理学通常显示小到中等血管淋巴细胞血管炎,与双边疾病不同.
结论:
- U-PACNS是一个未被认可的条件,非常重要.
- 及时的免疫抑制疗法对于预防误诊和不可逆转的神经缺陷至关重要.
- 识别U-PACNS有助于准确诊断和改善患者管理.
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