在前性研究中,用于复杂结石的单次访问迷你PCNL与灵活囊泡镜相比,多次访问迷你PCNL在前性研究中
Qing-Lai Tang1, Jun-Biao Ji2, Yun-Yun Tu2
1Department of Urology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, 211100, Jiangsu, China.
Scientific reports
|August 20, 2025
概括
通过灵活的囊镜进行单次接触的微创性皮肤内切除术 (MPCNL) 提供了更高的无结石率和复杂结石 (CRS) 的并发症减少. 这种方法是安全有效的,与多访问MPCNL相比,最大限度地减少损伤.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 最少侵入性的手术
- 脊髓石切除术 (nephrolithotomy) 是一个切除术.
背景情况:
- 复杂结石 (CRS) 在泌尿外科实践中是一个重大挑战.
- 最少侵入性皮肤穿神经切除术 (MPCNL) 是一种标准的治疗方法,但优化CRS的结果至关重要.
- 单次访问的MPCNL与灵活的囊镜相结合是一种新兴的技术.
研究的目的:
- 评估单次访问MPCNL与灵活囊泡镜的疗效和安全性与多次访问MPCNL治疗复杂结石 (CRS) 的疗效和安全性.
- 为了比较两种技术之间的无石头率 (SFR),手术时间,血液损失,住院和并发症.
主要方法:
- 一项前性随机对照试验,涉及195名CRS患者.
- 患者被随机分为两个组:单次访问的MPCNL (n=98) 和多次访问的MPCNL (n=97).
- 主要结局是SFR;次要结局包括手术时间,血红蛋白降低,住院和并发症.
主要成果:
- 单次访问的MPCNL在术后第二天和第四周显示出明显更高的SFR (P<0.05).
- 单次接入组的血红蛋白下降较少 (P<0.001),住院时间较短 (P<0.001).
- 复杂症的发生率,包括腰部疼痛,周围血瘤和动脉栓塞,在单次访问组显着较低 (P<0.05).
结论:
- 单次访问的MPCNL与灵活的囊镜相结合,是复杂结石 (CRS) 的有效和安全治疗方法.
- 这种技术可以实现高的无石头率,同时最大限度地减少损伤和并发症.
- 这种方法是可重复的,并且非常适合临床实践,与多访问MPCNL相比,它具有优势.
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