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Updated: Sep 10, 2025

Protein Purification Technique that Allows Detection of Sumoylation and Ubiquitination of Budding Yeast Kinetochore Proteins Ndc10 and Ndc80
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SAE2的HDAC6依赖性脱乙基化增强了SUMO1对线粒体完整性的结合

Alexander J Lanz1, Alexandra K Walker1, Mohammed Jamshad1

  • 1Birmingham Centre for Genome Biology and Department of Cancer and Genomic Sciences, School of Medical Sciences, College of Medicine and Health, University of Birmingham, Birmingham, B15 2TT, UK.

The EMBO journal
|August 20, 2025
PubMed
概括

线性忠实性依赖于SUMO1结合,由SUMO激活酶SAE1:SAE2.2的脱乙基化调节. 这一过程通过选择特定的SUMO蛋白质来确保适当的线粒细胞进展.

关键词:
乙化 乙化是一种E1 E1 E1 E1 E1 E1 E1 E1 E1 E1 E1 E1 E1 E1 E1 E1 E1 E1 E1在HDAC的基础上,HDAC是线粒分裂 (mitosis) 是一种发生在细胞间的过程.这就是SUMOylation的作用.

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