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Updated: Sep 10, 2025

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PARP7是一种蛋白质毒性应激传感器,它标记蛋白质进行降解

Nonso J Ikenga1, Jörg Vervoorts1, Bernhard Lüscher1

  • 1Institute of Biochemistry and Molecular Biology, RWTH Aachen University, Aachen, Germany.

The EMBO journal
|August 20, 2025
PubMed
概括

细胞ADP-ribosylation在蛋白质毒性压力期间增加,导致蛋白质聚合和通过自的降解. 抑制PARP7会破坏这个过程,突出显示它在应激反应中的作用.

关键词:
在ADP-ribosylation过程中.宏观领域是一个宏观领域.在PARP中,PARP是PARP.蛋白质降解 蛋白质降解在Ubiquitination中使用.

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