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Updated: Sep 10, 2025

Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method
08:04

Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method

Published on: October 23, 2018

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通过氨基酸对mTORC1的动态调节的结构基础

Max L Valenstein1,2,3,4, Maximilian Wranik5,6,7, Pranav V Lalgudi2,3

  • 1Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.

Nature
|August 20, 2025
PubMed
概括

对于生长至关重要的拉巴胺素复合物1 (mTORC1) 途径的机械性标受营养传感器的调节. 这项研究揭示了氨基酸传感器Sestrin2和CASTOR1如何与GATOR2复合体结合和调节,控制mTORC1的激活.

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Published on: June 6, 2025

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A RANKL-based Osteoclast Culture Assay of Mouse Bone Marrow to Investigate the Role of mTORC1 in Osteoclast Formation09:37

A RANKL-based Osteoclast Culture Assay of Mouse Bone Marrow to Investigate the Role of mTORC1 in Osteoclast Formation

Published on: March 15, 2018

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