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Updated: Apr 9, 2026

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用于骨组织工程中的向抗生素输送的刺激响应水凝

Jayendra Kumar1, Tolepbergenova M2, Abdugani Musayev2

  • 1Department of Pharmaceutical Chemistry, SRM Modinagar College of Pharmacy, SRM Institute of Science and Technology, Uttar Pradesh, Delhi-NCR Campus, Modinagar, Ghaziabad, 201204, India.

AAPS PharmSciTech
|August 21, 2025
PubMed
概括

具有刺激反应的水凝可为骨组织工程 (BTE) 提供受控的抗生素释放,解决感染挑战. 这些智能水凝增强愈合,血管化,

关键词:
生物活性脚手架骨组织工程对环境敏感的药物释放局部抗生素的使用智能生物材料对刺激有反应的水凝

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Modified-Release Drug Delivery Systems: Stimuli-Activated01:30

Modified-Release Drug Delivery Systems: Stimuli-Activated

Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also...
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