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供体母乳中的维生素A:一项实验研究

Amy Gates¹, Sarah D Maria², Nathan A Meredith²

¹Division of Neonatology, Department of Pediatrics, Children's Hospital of Georgia, Augusta, Georgia, USA.

JPEN. Journal of parenteral and enteral nutrition

|August 21, 2025

概括

捐赠人乳 (DHM) 的维生素A (视网醇) 含量可以变化. 对于一些纯母乳饮食的早产婴儿来说,标准强化可能无法提供足够的网膜醇.

科学领域:

营养科学
儿童营养
人类牛奶研究

背景情况:

对于无法接收母乳的婴儿来说,捐赠人乳 (DHM) 非常重要.
维生素A对婴儿的生长和发育至关重要.
确保早产婴儿摄入足够的营养是非常重要的.

研究的目的:

分析捐赠人母乳 (DHM) 中的维生素A (视网醇) 含量.
在接受强化DHM的早产婴儿中确定肠道维生素A摄入量.
评估目前维生素A供应的充足性.

主要方法:

从商业牛奶库收集的DHM样本 (n=15) 进行了视网醇含量分析.
使用超高性能液体染色学量化雷丁醇.
在使用商用人乳增强剂 (HMFs) 的标准增强方案的基础上计算了肠道网膜醇摄入量.

主要成果:

在DHM中的平均视网醇度为120±30IU/dL,具有显著的变异性 (49-158IU/dL).
在DHM中的红素含量与脂肪含量呈正相关性 (R2=0.37,P=0.01).
标准的HMF强化导致肠道视网醇摄入量范围广泛 (200-1600 IU/kg/天).

结论:

DHM中的维生素A含量与成熟的母乳相当.
目前的标准强化做法可能导致一些早产婴儿摄入不够的维生素A.
需要进行进一步的研究,以优化对易受伤害的婴儿群体的维生素A强化.

关键词:

强化剂人类牛奶营养问题过早出生甲基酸盐

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