在评估由黄蜂伤引起的多器官功能障碍综合征时,系统性免疫炎症指数和系统性炎症反应指数
Xiaolin Zhang1,2, Pengfei Liang1,2, Chi Tong1,2
1Department of Emergency Medicine, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, People's Republic of China.
Journal of inflammation research
|August 21, 2025
概括
早期的炎症标志物,全身免疫炎症指数 (SII) 和全身炎症反应指数 (SIRI),可以预测黄蜂患者的多器官功能障碍综合征 (MODS) 的发展. 这些指标为严重的黄蜂刺伤提供了有价值的预后见解.
科学领域:
- 紧急医疗
- 毒理学
- 免疫学
背景情况:
- 黄蜂刺伤可能导致严重的全身炎症反应.
- 多器官功能障碍综合征 (MODS) 是严重中毒的关键并发症.
- 早期预后标记对于管理MODS患者至关重要.
研究的目的:
- 评估黄蜂引起的MODS患者早期炎症指数的预后价值.
- 评估系统性免疫炎症指数 (SII) 和系统性炎症反应指数 (SIRI) 的预测准确性.
主要方法:
- 对151名黄蜂患者 (60名有MODS,91名没有) 的回顾性分析.
- 两组之间的早期外周血细胞计数衍生的炎症指数 (包括SII和SIRI) 的比较.
- 逻辑回归和ROC曲线分析以确定SII和SIRI的预测值.
主要成果:
- 在MODS和非MODS组之间,年龄,住院时间,刺痛严重程度,APACHE II分数和炎症指数 (SII,SIRI) 显著不同.
- 后勤回归发现SII和SIRI是预后的重要预测因素.
- 对SII和SIRI的AUC值分别为0. 776和0. 853,表明预测的准确性很好.
结论:
- 早期SII和SIRI值的升高与黄蜂伤的严重程度相关.
- SII和SIRI是预测黄蜂伤患者的MODS发展和死亡率的早期预测指标.
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