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Updated: Sep 10, 2025

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
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Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay

Published on: September 9, 2012

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低度的复合激活因子VII通过逆转abelacimabin vitro诱导的粘弹性测试参数的变化来使凝血模式正常化

Yasser Khder1, Serge Côté2, Klaus Peter Hoffmann3

  • 1Anthos Therapeutics, Cambridge, Massachusetts, USA.

Research and practice in thrombosis and haemostasis
|August 21, 2025
PubMed
概括

低剂量的复合活性因子VIIa (rFVIIa) 有效地逆转了FXI/ FXIa抑制剂阿贝拉西马布的抗凝固作用. 这表明rFVIIa可以控制abelacimab治疗的患者的出血.

关键词:
美国艾贝拉西马布抗凝固剂一个XIa因子抑制剂再组合的FVIIa

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