绘制证据和识别风险:对2型糖尿病中食用替代品的系统范围审查
Leong Chen Lew1,2, Arimi Fitri Mat Ludin1,3, Zahara Abdul Manaf1,4
1Centre for Healthy Ageing and Wellness, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Kuala Lumpur, Malaysia.
World journal of diabetes
|August 21, 2025
概括
当与生活方式干预相结合时,食用替代品有效控制2型糖尿病 (T2D) 和体重. 本综述强调了它们对血糖控制和BMI的安全性和益处.
科学领域:
- 内分泌学
- 代谢疾病
- 营养科学
背景情况:
- 二型糖尿病 (T2D) 是一个日益严重的全球健康问题,需要有效的管理策略.
- 生活方式的干预对于T2D管理至关重要,而食物替代品是常见的组成部分.
- 需要对2型糖尿病的食用替代品类型,剂量,结果和不良事件进行全面审查.
研究的目的:
- 对2型糖尿病患者的饮食替代品使用进行范围审查.
- 分析饮食替代干预的血糖和体重相关结果.
- 记录这些研究报告的不良事件的发生率和性质.
主要方法:
- 使用Arksey和O'Malley的框架进行范围审查.
- 在六个主要数据库中从2020年1月到2024年1月进行系统的文献搜索.
- 由两名研究人员进行独立的资格评估和数据提取,并由所有研究人员进行最终审查.
主要成果:
- 包括133项研究,按类型分类餐饮替代品 (低卡路里,低GI,富含蛋白质等). 和干预设计.
- 在血红蛋白A1c (59项研究) 和体重/BMI (70项研究) 中报告了显著的改善.
- 综合干预 (用辅导/教育代替餐) 显示出特别有效. 不良反应很少发生,大多是轻微的 (如便秘).
结论:
- 替代食是一种安全有效的T2D血糖和体重管理策略.
- 结合饮食替代剂与生活方式干预和辅导, 提高了它们的有效性.
- 进一步的研究可以完善T2D管理的最佳餐饮替代方案.
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