是A还是AB? 通过血清学评估解决较弱子组的困境:来自Uttarakhand的两例病例
Vaidehi Prasanth1, Pradip Banerjee1, Daljit Kaur1
1Department of Transfusion Medicine and Blood Bank, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Asian journal of transfusion science
|August 21, 2025
概括
这项研究报告了在献血者中发现的两例罕见的AB血型与弱B亚组 (ABel). 准确识别这些弱B子组对于预防输血反应至关重要.
科学领域:
- 输血医学
- 免疫学
- 遗传学
背景情况:
- 血型差异,特别是弱小组的血型差异, 构成诊断挑战.
- 像B3,Bx,Bm和Bel这样的罕见B亚组具有可变的血清反应性.
- 误解弱B亚组可能导致血型识别延迟或不正确.
研究的目的:
- 报告两例AB Rh (D) 阳性个体具有弱B子组.
- 突出诊断过程以识别罕见的血型变异.
- 强调精确的血液分组在输血医学中的重要性.
主要方法:
- 用标准抗血清对红细胞和血清进行血清检测.
- 用于抗体检测的吸附-疏散程序.
- 唾液测试以确认B抗原的存在.
主要成果:
- 两名全血献血者呈现出AB Rh (D) 阳性血型.
- 红细胞与抗A,抗AB和抗D结合,但与抗B没有反应.
- 对抗A1,抗A2,抗B和抗O的血清检测结果为阴性.
- 吸附-疏散和唾液测试证实了ABel亚组.
结论:
- 在两个捐赠者中成功识别了罕见的ABel亚组.
- 血型差异的准确解决,特别是弱小的B小组,至关重要.
- 预防血溶性输血反应依赖于精确的血型解释.
更多相关视频
相关概念视频
Blood Types
18.4K
Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...
18.4K
Blood Transfusion and Agglutination
13.2K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
13.2K
The ABO Blood Group
9.0K
The ABO blood group system is a critical element of transfusion medicine, essential for determining blood compatibility in transfusions and organ transplants. It is based on specific antigens, or agglutinogens, present on the surface of red blood cells (RBCs) and corresponding antibodies, or agglutinins, in the blood plasma.
Antigens in the ABO Blood Group System
Antigens are substances that can trigger an immune response, leading to the production of antibodies. In the ABO blood group system,...
Antigens in the ABO Blood Group System
Antigens are substances that can trigger an immune response, leading to the production of antibodies. In the ABO blood group system,...
9.0K
Rh Blood Group
4.4K
The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
4.4K
Blood Typing
6.2K
Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target...
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target...
6.2K
Blood Transfusion
3.0K
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
3.0K


