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Updated: Sep 10, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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Published on: March 15, 2024

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铁单原子酶介导的硫化输送放大了反应性氧物种级联,诱导了ferroptosis易感性

Xuegang Niu1,2,3, Penghui Wei1,2, Mingtao Zhu1,4

  • 1Department of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, 350005, China.

Materials today. Bio
|August 21, 2025
PubMed
概括

这项研究引入了一种新型的铁单原子酶纳米平台 (Fe/SAE@A),可增强癌细胞中的铁. 它提供硫化 (H2S) 抑制ROS清理,放大脂质过氧化和癌细胞死亡.

关键词:
催化疗法铁症硫化反应性氧物种一个原子酶

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