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成人先天性心脏病的并发症和多发症:基于多地点的人口研究的结果
Lorenzo D Botto1, Matthew R Reeder1, George K Lui2
1Department of Pediatrics, University of Utah, Salt Lake City, Utah, USA.
Birth defects research
|August 21, 2025
概括
患有先天性心脏病 (CHD) 的成年人经常出现多种并发症,特别是内分泌,代谢和神经精神疾病. 了解这些模式对于改善终身护理和预防这种不断增长的人口死亡至关重要.
科学领域:
- 心脏病学
- 公共卫生
- 成年人的先天性心脏病
背景情况:
- 随着先天性心脏病的生存率提高, 成年人数也在增加.
- 患有心血管疾病的成年人面临着许多影响治疗结果和护理的并发症.
- 成年人患有冠状动脉疾病的相关疾病数据有限,阻碍了预防工作.
研究的目的:
- 评估先天性心脏病的成年人的并发症的患病率和模式.
- 在该群体中确定常见的心脏和非心脏伴随性疾病.
- 根据社会人口统计学因素,探索并发症负担的变化.
主要方法:
- 这是一项针对美国18672名患有心脏病的成年人进行的基于人口的横截面研究.
- 2011-2013年间的临床和行政来源 (住院,门诊,急诊室) 的数据.
- 基于≥1个与心脏病相关的诊断代码进行纳入.
主要成果:
- 观察到并发症的高患病率:88. 5% 患有至少一种并发症,76% 患有多种并发症.
- 非心脏并发症比心脏病更频繁,包括内分泌/代谢 (糖尿病,高脂血症,甲状腺功能低下症),高血压和神经精神疾病.
- 随病率因社会人口统计学因素而异;男性和老年人患病率更高,不论是冠状动脉疾病类型.
结论:
- 在患有心血管疾病的成年人中,可预防的并发症和多发症非常普遍.
- 伴随性疾病模式受社会人口因素和心血管疾病类型的影响.
- 终身,协调,数据驱动的护理和健康指标跟踪对于降低死亡率至关重要.
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