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Updated: Sep 10, 2025

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses
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A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses

Published on: August 31, 2014

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精英中和体现型在HIV-1分类中的并行演化

Kathryn A Mesa1, Sophia W Li1,2, Jennie M Hutchinson1,3

  • 1Department of Biomolecular Engineering, Baskin School of Engineering, University of California Santa Cruz, Santa Cruz, California, USA.

Journal of virology
|August 21, 2025
PubMed
概括

艾滋病毒-1疫苗的开发依赖于了解广泛中和抗体 (bNAbs) 的演变. 这项研究揭示了HIV-1病毒群体中特定的甘氨酸进化对抗体的保护作用,影响中和范围,并为疫苗设计提供了见解.

关键词:
艾滋病毒-1进化生物学

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