在高度训练有素的男性长跑者中评估乌罗立A补充剂对跑步表现,恢复和线粒体生物标志物的影响
在PubMed上查看摘要
概括
此摘要是机器生成的。通过减少肌肉损伤和感知到的劳动力,乌罗立A (UA) 补充剂有助于男性跑步者的恢复,但没有改善跑步性能. 它还显示了线粒体的潜在益处.
科学领域
- 运动生理学
- 营养生物化学
- 线粒体生物学
背景情况
- 乌罗立A (UA) 是来自埃拉吉坦宁的肠道微生物代谢物.
- 之前的研究表明UA可以改善老年人的肌肉健康.
- 作为运动群体的 ergogenic 辅助 UA 的潜力.
研究的目的
- 研究UA补充剂对男性长跑者的耐力表现和生理适应的影响.
- 评估UA在高空训练期间对肌肉损伤,炎症和线粒体功能的影响.
主要方法
- 这是一项双盲,安慰剂对照的试验,对42名男子长途跑者进行了4周的高空跑.
- 补充每天1000毫克UA或安慰剂.
- 测量包括体质,血红蛋白质量,跑步经济,最大有氧能力和3000米计时.
- 肌肉活检分析蛋白质和线粒体变化;血液样本评估炎症和肌肉损伤标志物.
主要成果
- 补充UA并没有显著改善3000米计时赛的表现.
- 运动后UA显著降低了感知到的劳动力和肌肉损伤标志物 (肌酸激酶).
- 在UA患者群中观察到最大有氧容量 (VO2max) 的显著增加.
- 蛋白质组分析表明UA上调了线粒体通路和下调了骨肌肉中的炎症通路.
结论
- 通过减少炎症和肌肉损伤标志物,每天服用UA补充剂有助于恢复.
- 在训练有素的跑步者中,UA补充导致了有氧能力的提高和感知力的降低.
- 尽管生理上有所改善,但UA并没有提高该群体的整体跑步性能.
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