怀孕期间胎儿生长限制的超声波监测和围产期结果
Felicia V LeMoine1,2, Angela C Ranzini1,2, Marisa R Imbroane3
1Department of Reproductive Biology, 2559 Case Western Reserve University , Cleveland, OH, USA.
Journal of perinatal medicine
|August 21, 2025
概括
每周多普勒监测可持续的胎儿生长限制 (pFGR) 增加产科和新生儿并发症. 与pFGR怀孕的连续生长监测相比,这种方法没有降低围产死亡率.
科学领域:
- 产周医学
- 产妇和胎儿医学
- 新生儿学
背景情况:
- 对母亲和胎儿来说都存在重大风险.
- 目前对pFGR的监测策略有所不同,因此需要对其在管理周围不良结果方面的有效性进行比较.
研究的目的:
- 用每周多普勒监测和连续生长 (SG) 监测管理的pFGR来比较怀孕中的不良周围结果.
- 评估不同监测方法对母亲和新生儿发病率和死亡率的影响.
主要方法:
- 单个妊娠的回顾性队列研究pFGR (22 0/7 27 6/7 周,< 500g,≤10% 妊娠年龄).
- 第一个组:每周多普勒监视. 第二组 (SG):每3-4周进行一次生长评估.
- 围产期不良结果的比较,包括产科和新生儿综合结果.
主要成果:
- 每周多普勒监测组的慢性高血压,先前的胎儿死亡,估计胎儿体重< 3%,以及动脉多普勒异常的比率较高.
- 尽管周围死亡没有差异,但每周多普勒组的产科 (65. 4% vs 42. 7%) 和新生儿 (60. 8% vs 28. 4%) 复合不良结果率显著增加.
- 尽管每周监测组中某些风险因素的发生频率较高,但这些发现仍然存在.
结论:
- 在pFGR怀孕中,每周的多普勒监测与产科和新生儿发病率的增加有关.
- 在每周多普勒和SG监测组之间没有发现产周死亡率的显著差异.
- 这项研究的观察性限制了最终的解释,强调了进一步研究的必要性.
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