母性雌激素对合作繁殖哺乳动物的发育可塑性的代际影响
Britta Walkenhorst1, Ines Braga Goncalves2, Christine M Drea3
1Department of Evolutionary Biology and Environmental Studies, Animal Behaviour, University of Zurich, Switzerland; Center for the Interdisciplinary Study of Language Evolution (ISLE), University of Zurich, Switzerland.
Hormones and behavior
|August 21, 2025
概括
孕产妇的雌激素会影响毛猫的后代发育. 主导性母亲的后代表现出加快的声音发育,而从属性或抗雄激素治疗的母亲的后代则出现延迟,突出显示了激素对生命早期可塑性的影响.
科学领域:
- 行为生态学
- 内分泌学
- 哺乳动物的发育
背景情况:
- 发育的可塑性对于后代的生存和健康至关重要,使其能够适应环境的线索.
- 在野生哺乳动物中,尽管已知雌性雌激素变异,但对后代发育的孕产妇激素影响仍未得到充分研究.
- 猫 (Suricata suricatta) 是由于自然主导层次和声音交流而研究母体雌激素效应的模型.
研究的目的:
- 研究母体雌激素对幼子的声音发育可塑性的影响.
- 检查母亲的自然和实验性操纵的雄激素水平如何影响后代的生殖.
- 了解母体激素对后代社会生态条件的反应的作用.
主要方法:
- 记录和分析不同发育阶段的幼的发声.
- 从具有自然变异的雄激素水平的主导和附属母亲的后代进行比较.
- 在怀孕期间给主导母亲服用雄激素受体阻断剂,以实验性地改变雄激素暴露.
主要成果:
- 主导对照母的后代表现出加速的声音发育,在不利条件下表现出弹性.
- 从下属对照和接受抗雄激素治疗的母亲的后代表现出声音发育的遗传延迟.
- 暴露于抗雄激素的后代表现出性别特异的声道轨迹和非典型的早期呼叫,表明对环境因素的敏感性增加.
结论:
- 孕产妇的雌激素在哺乳动物后代的发育和声乐可塑性中起着重要作用.
- 后代的声音发育轨迹对母亲的荷尔蒙环境和社会生态压力敏感.
- 这项研究提供了母亲对后代发育中介的罕见证据,以应对环境需求.
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