引起乳腺炎的病原体 (大肠杆菌和金黄色葡萄球菌) 对作为乳头浸泡剂使用的消毒剂的敏感性
Marcilene Daniel Damasceno1, Maysa Serpa Gonçalves1, Bruna Henrique Pinto da Silva1
1Universidade Federal de Lavras, Faculdade de Zootecnia e Medicina Veterinária, Departamento de Medicina Veterinária, Lavras, MG, Brazil.
Veterinary microbiology
|August 21, 2025
概括
暴露于乳头消毒剂的奶牛对常见的乳腺炎病原体如大肠杆菌和黄金葡萄球菌产生了耐药性. 这种对消毒剂的敏感性降低对动物和公众健康构成风险.
科学领域:
- 动物医学
- 微生物学
- 动物健康
背景情况:
- 乳腺炎是奶牛养殖中的重要经济疾病.
- 大肠杆菌和金黄色葡萄球菌是主要的乳腺炎病原体.
- 乳腺消毒剂用于预防乳腺炎,但可能导致抗菌药物耐药性.
研究的目的:
- 在实验室中评估引起乳腺炎的金黄色葡萄球菌和大肠杆菌对常用的乳头浸泡消毒剂的敏感性.
- 评估持续接触消毒剂是否有助于降低病原体的敏感性.
主要方法:
- 病原体分离物 (S. aureus,大肠杆菌) 进行了对六种消毒剂的测试:过氧化,低酸,二氧化,乳酸,四级和.
- 用苏微稀释来确定每个消毒剂对每个病原体的最小抑制度 (MIC).
- 根据隔离年份进行分离分析,以追踪随时间的敏感性变化.
主要成果:
- 大多数大肠杆菌和黄金杆菌菌株对二甲酸,过氧化,,乳酸和四级的度低于现场使用的度敏感.
- 大肠杆菌 (80. 77%) 和金色杆菌 (34. 5%) 的显著百分比对推度的敏感性降低.
- 最近几年的病原体分离物与较古老的分离物相比,对大多数测试消毒剂的耐受性增加,除了二氧化.
结论:
- 在奶牛养殖中持续接触乳头消毒剂会选择易感性降低的大肠杆菌和金黄色细菌菌株.
- 减少对消毒剂,特别是酸盐的敏感性是一个越来越令人担忧的问题.
- 这种现象对乳腺炎的控制构成重大挑战,影响动物和公共健康.
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